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Braz. dent. j ; 18(3): 198-201, 2007. ilus
Article in English | LILACS | ID: lil-471440

ABSTRACT

The aim of this study was to investigate the effect of gallium nitrate solution, an anti-resorption substance, when applied for root surface treatment in rat teeth submitted to delayed replantation, in order to inhibit the root resorption process and enhance repair. For such purpose, 20 maxillary right central incisors of rats were randomly assigned to 2 groups (n=10). In group I, root surface was treated with 10-4M gallium nitrate solution for 20 min, while in group II root surface was treated with 2 percent sodium fluoride for 20 min. All root canals were filled with a calcium hydroxide-based paste. At 15 and 60 days after replantation, the animals were killed and the specimens were processed in laboratory for light transmission microscopy. In both groups, there was mild occurrence of ankylosis and root resorption. The connective tissue formed at the periodontal ligament area was arranged parallel to the root in most specimens in both groups and presented signs of inflammation. In group I, there was periodontal pocket formation in all specimens at 60 days, revealing lack of repair. These findings contraindicate the use of gallium nitrate for root surface treatment of teeth submitted to late replantation.


Este trabalho teve como objetivo testar o efeito da solução de nitrato de gálio, uma substância anti-reabsortiva, quando usada no tratamento da superfície radicular de dentes reimplantados tardiamente, com o intuito de inibir o processo de reabsorção radicular e facilitar o reparo. Para isso, foram utilizados 20 incisivos centrais superiores direitos de ratos, divididos em 2 grupos (n=10). No grupo I, a superfície radicular foi tratada com solução de nitrato de gálio a 10-4M por 20 min e no grupo II com fluoreto de sódio a 2 por cento por 20 min. Todos os canais foram preenchidos com pasta de hidróxido de cálcio. Após 15 e 60 dias do reimplante, os animais foram mortos e as peças obtidas, processadas em laboratório para análise em microscópio de transmissão de luz. Em ambos os grupos, houve pequena ocorrência de anquilose e reabsorção radicular. O tecido conjuntivo formado no espaço do ligamento periodontal disposto paralelamente à raiz, na maioria dos espécimes dos dois grupos, mostrou-se inflamado e com algumas áreas de necrose. No grupo I, houve a formação de bolsa periodontal em todos os espécimes aos 60 dias, indicando a ausência de reparo. Estes achados desaconselham o uso do nitrato de gálio para o tratamento de superfície de dentes reimplantados tardiamente.


Subject(s)
Animals , Male , Rats , Gallium/administration & dosage , Immunosuppressive Agents/administration & dosage , Root Resorption/prevention & control , Tooth Replantation , Tooth Root/drug effects , Administration, Topical , Fluorides, Topical , Incisor , Maxilla , Random Allocation , Rats, Wistar , Surface Properties , Sodium Fluoride/administration & dosage , Time Factors , Tooth, Nonvital , Treatment Outcome , Tooth Ankylosis/prevention & control , Wound Healing/drug effects
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